Table 3.

BSEP Inhibition Assay Associated With DILI (Dawson et al., 2012; Dataset)

Weak Inhibitors Included as BSEP-Inhibitors
Criteria	% of Drugs With DILI Predicted Correctly, PPV	% of DILI Missing in the Prediction, FNR	% of DILI Predicted Accurately, ACC (n = 82)
BSEP (Strong and Weak Inhibitors)	84.2%	49.2%	54.9%
BDDCS class 2	88.2%	52.4%	54.9%
Weak Inhibitors Excluded
Criteria	% of Drugs with DILI Predicted Correctly, PPV	% of DILI Missing in the Prediction, FNR	% of DILI Predicted Accurately, ACC (n = 76)
BSEP (Strong Inhibitors)	87.5%	52.5%	53.9%
BDDCS class 2	89.7%	55.9%	52.6%