Skip to main content
. 2017 Dec 1;162(2):548–558. doi: 10.1093/toxsci/kfx275

Table 1.

Hepatic Fatty Acid Profiles

Fold of Change
Subpathway Biochemical Name PCB126 vs. VEH
Medium chain fatty acid Caproate (6: 0) 1.967
5-Dodecenoate (12: 1n7) 1.1949
Long chain fatty acid Myristate (14: 0) 1.6483
Myristoleate (14: 1n5) 1.5047
Pentadecanoate (15: 0) 1.3333
Palmitate (16: 0) 1.4202
Palmitoleate (16: 1n7) 1.689
Margarate (17: 0) 1.8135
10-Heptadecenoate (17: 1n7) 2.1296
Stearate (18: 0) 1.3224
Oleate/vaccenate (18: 1) 1.8901
Nonadecanoate (19: 0) 1.7897
10-Nonadecenoate (19: 1n9) 2.4285
Arachidate (20: 0) 2.1044
Eicosenoate (20: 1) 3.4008
Behenate (22: 0)* 1.4465
Erucate (22: 1n9) 2.8541
Nervonate (24: 1n9)* 1.3063
Polyunsaturated fatty acid (n3 and n6) Heneicosapentaenoate (21: 5n3) 3.933
Hexadecadienoate (16: 2n6) 2.2067
Stearidonate (18: 4n3) 1.5706
Eicosapentaenoate (EPA; 20: 5n3) 1.2174
Docosapentaenoate (n3 DPA; 22: 5n3) 1.985
Docosahexaenoate (DHA; 22: 6n3) 1.2193
Docosatrienoate (22: 3n3) 2.5254
Nisinate (24: 6n3) 1.211
Linoleate (18: 2n6) 1.835
Linolenate [alpha or gamma; (18: 3n3 or 6)] 1.8176
Dihomo-linolenate (20: 3n3 or n6) 2.5076
Arachidonate (20: 4n6) 1.1887
Adrenate (22: 4n6) 1.3929
Docosapentaenoate (n6 DPA; 22: 5n6) 1.3923
Docosadienoate (22: 2n6) 2.6117
Dihomo-linoleate (20: 2n6) 3.0053
Mead acid (20: 3n9) 1.2317
Docosatrienoate (22: 3n6)* 1.8835
Fatty acid, branched 15-Methylpalmitate (i17: 0) 1.5624
17-Methylstearate (i19: 0) 1.7984

Hepatic fatty acid methyl esters were quantitated and significant differences were determined by Welch’s two-sample t-tests. Red shading and bold values denotes significantly increased lipid abundance in PCB 126-treated mice (fold change compared to Vehicle; p < .05).