n |
Number of haplotypes with the selected allele |
m |
Number of haplotypes without the selected allele |
L |
Number of SNPs flanking the selected site (one side considered at a time) |
X |
n × L matrix of haplotypes with the selected allele |
H |
m × L matrix of haplotypes without the selected allele |
Xij |
Allele in haplotype i at SNP j, where , and
|
Hzj |
Allele in haplotype z at SNP j, where , and
|
Aj |
Allele at site j on the ancestral haplotype |
Zij |
The reference panel haplotype from which Xi copies at site j
|
tca
|
Time to the most recent common ancestor (TMRCA) |
Wi |
The location of the first recombination event off of the ancestral haplotype |
r |
Recombination rate per basepair per generation |
μ |
Mutation rate per basepair per generation |
θ |
Haplotype miscopying rate, or population-scaled mutation rate
|
ρ |
Haplotype switching rate, or population-scaled recombination rate
|
dw |
Physical distance of site w from the selected site, where
|
cj |
Number of basepairs between sites j and j + 1 |
αiw |
Likelihood of haplotype i for sites
|
βiw |
Likelihood of haplotype i for SNPs
|