Table 4.

Intervention Parameter Estimates

Parameter		Baseline Mean (Range)	Enhanced Mean (Range)	Ideal Mean	Sourcea
Hand hygiene
Soap and water effectiveness		96 (90–100)			[102–104]
ABHR effectiveness		29 (13–36)			[92, 103]
Standard Room Compliance	Nurse	60 (46–68)	79 (74–84)	96	[105–115]
	Doctor	50 (40–55)	71 (57–80)	91	[105–117]
	Visitor	35 (20–50)	55 (50–67)	84	[106, 118–124]
	Patient	33 (30–40)	59 (55–65)	84	[120, 125–129]
	Fraction soap and water (vs ABHR)	10 (5–25)			[110, 130]
Known C. difficile Room Compliance	Nurse	69b	84b	97	[59, 131–133]
	Doctor	61b	77b	93	[59, 131–133]
	Visitor	50b	65b	88	[59, 131–133]
	Patient	48b	68b	88	[59, 131–133]
	Fraction soap and water (vs ABHR)	80 (70–90)	90 (80–95)	95	[134]
Contact precautions
Gown and glove effectiveness		70 (60–80)	86 (80–90)	97	[135–137]
Healthcare worker compliance		67 (62–72)	77 (71–85)	87	[59, 118, 138–142]
Visitor compliance		50 (42–52)	74 (70–80)	94	[118, 138, 139]
Environmental cleaning
Daily cleaning compliance		46 (40–50)	80 (70–85)	94	[29–33]
Terminal cleaning compliance		47 (40–50)	77 (70–82)	98	[29, 143–146]
Nonsporicidal effectiveness		45 (35–50)			[147, 148]
Sporicidal effectiveness		99.6			[148–151]
Asymptomatic screening at admission
Compliance		0	96 (92–99)	98	[38, 152]
PCR test sensitivity; specificity		93 (90–94); 97 (95–99)			[153–155]
Patient transfer
Intraward transfer rate		5.7 (4–7.4)	2.8 (2.2–3.5)	1.4	Internal data
Interward transfer rate		13.7 (10–17.4)	6.8 (5–8.7)	3.4	Internal data
Proportionate time between transfers		24% (time between transfer/length of stay; 20–30)			Internal data

Abbreviations: ABHR, alcohol-based hand rub; C.difficile, Clostridium difficile; PCR, polymerase chain reaction.

^aReferences for input parameter sources are included in the Supplementary Materials.

^bKnown Clostridium difficile room compliance range based on the range in standard room and standard:C. difficile infection hand hygiene noncompliance ratio (1.34).