Table 6.
Comparative Clinical Effectiveness of 8 Multiple-Intervention Bundles
| Bundle Components | HO-CDI per 10000 Patient-days (95% CI) | Asymptomatic Colonization per 1000 Admissions (95% CI) |
|---|---|---|
| Baseline | 7.98 (7.95–8.02) | 32.51 (32.44–32.57) |
| Patient and HCW HH | 4.74 (4.71–4.77) | 17.33 (17.29–17.38) |
| Terminal and daily cleaning | 2.44 (2.41–2.46) | 6.96 (6.93–6.99) |
| Screening, patient HH, patient transfer | 3.75 (3.73–3.78) | 13.14 (13.09–13.19) |
| Daily cleaning, surveillance | 1.41 (1.39–1.43) | 3.05 (3.03–3.07) |
| Daily cleaning, surveillance, HCW HH | 1.18 (1.17–1.20) | 2.00 (1.99–2.01) |
| Daily cleaning, surveillance, HCW HH, patient HH | 1.13 (1.11–1.14) | 1.67 (1.66–1.68) |
| Daily cleaning, surveillance, HCW HH, patient HH, terminal cleaning | 1.12 (1.10–1.13) | 1.61 (1.60–1.62) |
| Daily cleaning, surveillance, HCW HH, patient HH, terminal cleaning, patient transfer | 1.11 (1.10–1.12) | 1.59 (1.57–1.60) |
Comparative effectiveness of 8 multiple-intervention combination bundles.
Abbreviations: CI, confidence interval; HCW, healthcare worker; HH hand hygiene; HO-CID, hospital-onset Clostridium difficile infection.