Figure 1.

3D brain renderings showing results of FDG-PET analysis in tau-negative patients. Results are shown at P(unc) = 0.001 with the height cut-off for family-wise error (FWE) correction shown in the colour bar. (A) Compared to controls, tau-negative amyloid-negative participants had hypometabolism in the posterior and middle cingulate and the medial temporal lobes. (B) Compared to controls, tau-negative amyloid-positive participants also had hypometabolism in the posterior and middle cingulate and the medial temporal lobes. (C) Conjunction analysis of A and B revealing areas involved in both amyloid-positive and amyloid-negative cases compared to controls. Renders created using Brain Net Viewer (Xia et al., 2013) (https://www.nitrc.org/projects/bnv/).