Table 2.
Demographic and pathology data for autopsy cohort
| Hippocampal sclerosis | Alzheimer’s disease | |
|---|---|---|
| (n = 8) | (n = 10) | |
| Demographics | ||
| Sex, male/female | 3/5 | 7/3 |
| Age at FDG-PET (Q1, Q3) | 83 (79.25, 84.75) | 83 (79.25, 84.75) |
| Duration at FDG-PET (Q1, Q3)a | 7 (2.5, 9) | 7.5 (6, 9.75) |
| Age at death (Q1, Q3) | 89 (86.75, 93) | 87.5 (82.5, 89.5) |
| Level of Alzheimer’s disease pathological changes | ||
| Not Alzheimer’s | 1 | 0 |
| Low | 0 | 0 |
| Intermediate | 5 | 3 |
| High | 2 | 7 |
| ABC | ||
| A0B1C0 | 1 | 0 |
| A3B5C2 | 2 | 1 |
| A3B6C2 | 0 | 2 |
| A4B3C2 | 1 | 0 |
| A4B4C2 | 2 | 0 |
| A4B6C2 | 0 | 1 |
| A5B5C2 | 1 | 1 |
| A5B6C2 | 1 | 5 |
Count data are reported, except for age and duration where median and interquartile range (Q1, Q3) are reported. There were no statistically significant differences for sex (P = 0.3416), age at PET (P = 0.4449), duration at PET (P = 0.5168) or age at death (P = 0.2289) between groups. The level of Alzheimer’s disease neuropathological change and ABC staging are reported according to NIA-AA guidelines (Hyman et al., 2012).
aData not available for four Alzheimer’s disease and one hippocampal sclerosis participants.