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. Author manuscript; available in PMC: 2019 Jan 11.
Published in final edited form as: J Med Chem. 2017 Oct 27;61(1):84–97. doi: 10.1021/acs.jmedchem.7b00932

Figure 8.

Figure 8

Protection of hearing in Fischer 344 rats treated with amikacin (320mg/kg/day s.c.) for 12 days with or without concurrent oral administration of 90 (5 mg/kg/day). Threshold shift from pre-treatment hearing levels at 2-weeks following treatment period.