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. Author manuscript; available in PMC: 2019 Jan 11.
Published in final edited form as: J Med Chem. 2017 Oct 27;61(1):84–97. doi: 10.1021/acs.jmedchem.7b00932

Table 3. Urea variants.

Protective activity of 2-aminothiophene variants in the zebrafish hair cell protection assay. NA – not active (HC50 > 25 μM).

graphic file with name nihms953119u4.jpg X HC50 (μM)
1 graphic file with name nihms953119t27.jpg 3.12
26 graphic file with name nihms953119t28.jpg 6.57
27 graphic file with name nihms953119t29.jpg NA
28 graphic file with name nihms953119t30.jpg NA
29 graphic file with name nihms953119t31.jpg NA
30 graphic file with name nihms953119t32.jpg NA
31 graphic file with name nihms953119t33.jpg NA
32 graphic file with name nihms953119t34.jpg NA
33 graphic file with name nihms953119t35.jpg NA