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Protective activity of bicyclic tetrahydropyridine (tropane) analogues in the zebrafish hair cell protection assay.
| Compound | R | HC50 (μM) |
|---|---|---|
| 1 |
|
3.12 |
| 87 |
|
1.24 |
| 89 |
|
2.25 |
| 90 |
|
0.12 |
| 92 |
|
7.21 |
| 93 |
|
0.27 |
| 95 |
|
3.92 |
| 96 |
|
0.27 |
| 98 |
|
5.00 |
| 99 |
|
0.03 |
