Table 5.
Study Cohort | Validation Cohort | |||
---|---|---|---|---|
FO grade | ≥2 (n=28) | <2 (n=112) | ≥2 (n=26) | <2 (n=412) |
D100 NRM cases | 10 (%) | 3 (%) | 8 (%) | 14 (%) |
Cause of NRM | ||||
Graft failure | 1 (10) | 1 (33) | 1 (13) | 1 (7) |
Infection | 3 (30) | 2 (67) | 2 (25) | 3 (21) |
Acute GVHD | 1 (10) | 0 | 3 (38) | 5 (36) |
Organ failure | 2 (20) | 0 | 0 | 2 (14) |
Hemorrhage | 1 (10) | 0 | 1 (13) | 0 |
ARDS | 2 (20) | 0 | 0 | 0 |
Pneumonia | 1 (13) | 1 (7) | ||
Secondary malignancy | 0 | 1 (7) | ||
Other | 0 | 1 (7) |
NRM, non-relapse mortality; FOR, fluid overload/retention; GVHD, graft-versus-host disease; ARDS, adult respiratory distress syndrome.