Table 3. Multivariate analyses for target failure-free survival, in-lobe failure-free survival, regional failure-free survival, distant metastasis failure-free survival, progression-free survival, and overall survival.
Multivariate Analysis | Overall survival | Target failure-free survival | ||
Factors | HR (95% CI) | P Value | HR (95% CI) | P Value |
Age | ||||
At SBRT | - | - | - | - |
At diagnosis | 1.02 (1.01-1.04) | 0.01 | - | - |
Tumor Size | 1.30 (0.97-1.75) | 0.08 | 1.87 (1.10-3.12) | 0.02 |
Primary Origin | ||||
Breast | Reference | Reference | ||
Esophagus | 3.56 (0.84-15.1) | 0.09 | 1.35 (0.13-13.7) | 0.80 |
GYN | 1.28 (0.29-5.57) | 0.75 | 0.05 (0.00-1.20) | 0.07 |
Head/Neck | 1.84 (0.51-6.58) | 0.35 | * | 0.97 |
Sarcoma | 3.63 (0.87-15.2) | 0.08 | 0.63 (0.05-7.92) | 0.72 |
GU | 0.69 (0.17-2.91) | 0.62 | 1.32 (0.11-16.0) | 0.83 |
Colorectal | 0.86 (0.26-2.85) | 0.80 | 1.17 (0.28-7.24) | 0.68 |
Melanoma | 1.33 (0.28-6.29) | 0.72 | * | 0.99 |
Other | 0.57 (0.10-3.40) | 0.54 | * | 0.99 |
Number lesions at SBRT | - | - | 0.26 (0.04-1.80) | 0.17 |
BED10 | 0.99 (0.985-0.999) | 0.02 | 0.98 (0.96-0.997) | 0.02 |
Multivariate Analysis | In-lobe failure-free survival | Regional failure-free survival | ||
Factors | HR (95% CI) | P Value | HR (95% CI) | P Value |
Tumor Size | 1.41 (1.17-1.70) | <0.001 | - | - |
Number lesions at SBRT | - | - | 0.49 (0.31-0.76) | 0.001 |
BED10 | - | - | 0.99 (0.98-0.997) | 0.003 |
Time to 1st SBRT | - | - | 0.99 (0.985-0.999) | 0.02 |
Post SBRT Chemotherapy | 2.08 (1.10-3.91) | 0.02 | - | - |
Multivariate Analysis | Distant metastasis failure-free survival | Progression-free survival | ||
Factors | HR (95% CI) | P Value | HR (95% CI) | P Value |
Number lesions at SBRT | 0.56 (0.38-0.82) | 0.003 | 0.56 (0.44-0.72) | <0.001 |
Post SBRT Chemotherapy | 2.65 (1.49-4.71) | <0.001 | 2.61 (1.72-3.98) | <0.001 |