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. 2018 Feb 7;10(2):e2167. doi: 10.7759/cureus.2167

Table 3. Multivariate analyses for target failure-free survival, in-lobe failure-free survival, regional failure-free survival, distant metastasis failure-free survival, progression-free survival, and overall survival.

stereotactic body radiation therapy (SBRT), genitourinary (GU), gynecologic (GYN), biologically effective dose with alpha-beta ratio of 10 (BED10)

Multivariate Analysis Overall survival   Target failure-free survival  
Factors HR (95% CI) P Value HR (95% CI) P Value
Age        
At SBRT - - - -
At diagnosis 1.02 (1.01-1.04) 0.01 - -
Tumor Size 1.30 (0.97-1.75) 0.08 1.87 (1.10-3.12) 0.02
Primary Origin        
Breast Reference   Reference  
Esophagus 3.56 (0.84-15.1) 0.09 1.35 (0.13-13.7) 0.80
GYN 1.28 (0.29-5.57) 0.75 0.05 (0.00-1.20) 0.07
Head/Neck 1.84 (0.51-6.58) 0.35 * 0.97
Sarcoma 3.63 (0.87-15.2) 0.08 0.63 (0.05-7.92) 0.72
GU 0.69 (0.17-2.91) 0.62 1.32 (0.11-16.0) 0.83
Colorectal 0.86 (0.26-2.85) 0.80 1.17 (0.28-7.24) 0.68
Melanoma 1.33 (0.28-6.29) 0.72 * 0.99
Other 0.57 (0.10-3.40) 0.54 * 0.99
Number lesions at SBRT - - 0.26 (0.04-1.80) 0.17
BED10 0.99 (0.985-0.999) 0.02 0.98 (0.96-0.997) 0.02
Multivariate Analysis In-lobe failure-free survival   Regional failure-free survival  
Factors HR (95% CI) P Value HR (95% CI) P Value
Tumor Size 1.41 (1.17-1.70) <0.001 - -
Number lesions at SBRT - - 0.49 (0.31-0.76) 0.001
BED10 - - 0.99 (0.98-0.997) 0.003
Time to 1st SBRT - - 0.99 (0.985-0.999) 0.02
Post SBRT Chemotherapy 2.08 (1.10-3.91) 0.02 - -
Multivariate Analysis Distant metastasis failure-free survival   Progression-free survival  
Factors HR (95% CI) P Value HR (95% CI) P Value
Number lesions at SBRT 0.56 (0.38-0.82) 0.003 0.56 (0.44-0.72) <0.001
Post SBRT Chemotherapy 2.65 (1.49-4.71) <0.001 2.61 (1.72-3.98) <0.001