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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Differentiation. 2018 Feb 2;100:21–25. doi: 10.1016/j.diff.2018.01.004

Figure 2.

Figure 2

Binding competition between shelterin and TZAP regulates telomere trimming. Telomere elongation beyond the optimal upper threshold results in reduced shelterin binding, allowing TZAP to bind telomeres to reset the upper limit of telomere length.