Figure 1. Basal amylin has no effect on myocyte Ca²⁺ cycling.

(A–B) Representative recordings of Ca²⁺ transients triggered at 0.2, 0.5, 1 and 2 Hz in cardiac myocytes from male (A) and female (B) WT and AKO mice. (C) Ca²⁺ transient amplitudes in cardiac myocytes from male WT mice (10 cells, 4 mice) vs. male AKO mice (11 myocytes, 4 mice). (D) Ca²⁺ transient amplitudes in cardiac myocytes from female WT mice (11 cells, 4 mice) vs. female AKO mice (13 myocytes, 3 mice). (E-F). The decline time of Ca²⁺ transients triggered by excitation at 0.5 Hz in myocytes from male (C) and female (D) WT and AKO mice. In all groups, data were recorded from 2–3 myocytes/mouse and are presented as the mean±SEM for myocytes.