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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2017 Dec 16;31(3):432–436. doi: 10.1111/pcmr.12674

Table 1. Genomic and pathologic details of tumors harboring BRAF internal deletions.

Disease Ontology N-Ras Mutations K-Ras Mutations B-Raf Mutations BRAF Exons Deleted
unknown primary melanoma ND ND V600 K601>E 2-8
unknown primary melanoma ND ND V600E 4-8
unknown primary melanoma ND ND V600K 2-10
unknown primary melanoma ND ND ND 2-10
unknown primary melanoma ND ND V600E 3-10
skin melanoma ND ND V600E 2-8
skin melanoma ND ND T599I 3-8
skin melanoma ND ND V600E 2-8
head and neck melanoma ND ND L597S 2-8
vulva melanoma ND ND D594G 3-8
bladder urothelial (transitional cell) carcinoma ND ND D587H 3-8
bone marrow multiple myeloma ND ND V600E 2-8
bone marrow multiple myeloma ND ND V600E 2-8
bone marrow multiple myeloma ND ND ND 2-10
brain glioblastoma ND ND ND 3-8
breast carcinoma (nos) ND ND ND 4-7
breast invasive ductal carcinoma ND ND ND 5-9
lung adenocarcinoma ND G12C ND 2-9
lung non-small cell lung carcinoma ND ND D594G 4-8
lung non-small cell lung carcinoma ND ND G464A 4-8
nasopharynx and paranasal sinuses carcinoma ND ND L485F 3-8
pancreas ductal adenocarcinoma ND ND S467L 2-10
prostate acinar adenocarcinoma ND ND ND 4-8
thymus thymoma ND ND ND 3-10
unknown primary adenocarcinoma ND ND ND 2-7
unknown primary germ cell tumor ND amplification ND 3-8

ND: Not detected. NOS: Not otherwise specified