. Author manuscript; available in PMC: 2019 May 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2018 May 1;78(1):54–61. doi: 10.1097/QAI.0000000000001641

Table 3.

A. Predictors of hepatotoxicity using multivariate logistic regression (N=410)^*
Characteristics	Hepatotoxicity		Odds Ratio	95% CI	P-value
	Yes (n=30)	No (n=380)
Hepatitis B surface antigen
Negative	23 (6%)	361 (94%)	1
Positive	7 (27%)	19 (73%)	4.7	1.7–12.9	0.002
Pretreatment AST/ALT^†
Normal	15 (5%)	312 (95%)	1
Raised	16 (16%)	83 (84%)	3.6	1.7–7.7	0.001
B. Univariate logistic regression for the combined variable for raised pretreatment AST/ALT and HBsAg positive at baseline (N=410)^*
Neither raised AST/ALT nor HBsAg positive	12 (4%)	287 (96%)	1
Raised AST/ALT only or HBsAg positive only	13 (13%)	87 (87%)	3.4	1.5–7.3	0.003
Both raised AST/ALT and HBsAg positive	5 (45%)	6 (55%)	19.9	5.3–74.3	<0.001

16 results were not obtained