Fig. 6.

Genes of different genome evolution patterns have different PPIs. a The mean number of CNSs linked to different synteny and duplication related gene sets. The ‘*’ above each column indicates P < 0.001. b The association between CNSs and protein–protein interactions in Populus and Arabidopsis for CNSs. The trend represents a significant positive correlation between CNS number and interactions, where R is the Pearson correlation coefficient, and P is the upper tail probability that the true correlation is greater than zero. Error bars, bootstrap-based 95% confidence intervals on the mean estimates. Statistical inference is conducted with a permutation test on the mean (perm.test in the R package exact RankTests)