Fig. 4.

Inflammatory mediators and immune cells in the fracture hematoma 3 h and 1 day after fracture (Fx) and combined fracture and thoracic trauma (Fx + TxT) in vehicle-, anti-IL-6 antibody-, and sgp130Fc-treated mice. Data are displayed as means ± standard deviation. a IL-6, b MCP-1 monocyte chemotactic protein 1, and c CXCL1 chemokine (C-X-C motif) ligand 1 concentrations after 3 h. d Proportion of neutrophils (CD11b+, Ly6G+), e macrophages (CD11b+, F4/80+), f B cells (CD19+), and g T cells (CD3+). a–c n = 6–7, d n = 6–8, e–g n = 7–8. **p ≤ 0.01, ***p ≤ 0.001