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. 2018 Apr 6;5(2):ENEURO.0080-18.2018. doi: 10.1523/ENEURO.0080-18.2018

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Copyright © 2018 Baker et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — Modulation of basal Ca²⁺ transients by cholinergic input. A, Representative ST maps showing the effects of atropine (1 μM) on basal Ca²⁺ transient activity in ICC-DMP. B–E, Summary graphs showing the effect of atropine on the frequency (B), amplitude (C), duration (D), and spatial spread (E) of basal Ca²⁺ transients in ICC-DMP (n = 5, c = 13). F, Representative ST maps showing the effects of ACh (10 μM; in the presence of TTX) on Ca²⁺ transients in ICC-DMP. G–J, Summary graphs showing the effect of ACh (in the presence of TTX) on the frequency (G), amplitude (H), duration (I), and spatial spread (J) of Ca²⁺ transients in ICC-DMP (n = 5, c = 9); ns = p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001.