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. 2018 Apr 6;5(2):ENEURO.0080-18.2018. doi: 10.1523/ENEURO.0080-18.2018

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Copyright © 2018 Baker et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 6. — Effects of neurokinin receptor (NK1) antagonists on basal Ca²⁺ transients. A, Representative ST maps showing the inhibitory effects of the NK1 receptor antagonist, RP 67580 (1 μM), on Ca²⁺ transients in ICC-DMP. B–E, Summary graphs showing the effects of RP 67580 on the frequency (B), amplitude (C), duration (D), and spatial spread (E) of Ca²⁺ transients in ICC-DMP (n = 11, c = 27). F, Representative ST maps showing the inhibitory effects of the NK1 receptor antagonist, SR 140333 (1 μM), on Ca²⁺ transients in ICC-DMP. G–J, Summary graphs showing the effects of 1 μM SR 140333 on the frequency (G), amplitude (H), duration (I), and spatial spread (J) of Ca²⁺ transients in ICC-DMP (n = 4, c = 14); ns = p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001.