Table 6.
Measure | 3 gene RT-PCR panel (Total cases to total controls) | 3 gene RT-PCR panel (Gross hematuria cases to gross hematuria controls) | ||
---|---|---|---|---|
Point estimation (%) | 95% CI | Point estimation (%) | 95% CI | |
Sensitivity | 83.6 | 83.6 | 81.8 | 48.2, 97.7 |
Specificity | 61.4 | 61.4 | 80.0 | 28.4, 99.5 |
ROC area | 0.725 | 0.725 | 0.809 | 0.5, 1.0 |
+LR | 2.1 | 2.1 | 4.0 | 1.2, 13.6 |
-LR | 0.2 | 0.2 | 0.2 | 0.06, 0.8 |
DOR | 8.0 | 8.0 | 18.0 | 1.5, 213 |
PPV | 73.4 | 73.4 | 82.8 | 59.0, 94.1 |
NPV | 74.6 | 74.6 | 78.9 | 51.4, 93.0 |
+LR, positive likelihood ratio; -LR, negative likelihood ratio; DOR, ROC area and diagnostic odds ratio; PPV, positive predictive value; NPV, negative predictive value