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. 2018 May;22(3):160–170. doi: 10.22034/ibj.22.3.160

Table 6.

The 3 gene RT-PCR panel Diagnostic test performance indicators scores in total cases to total controls and gross hematuria cases to gross hematuria controls

Measure 3 gene RT-PCR panel (Total cases to total controls) 3 gene RT-PCR panel (Gross hematuria cases to gross hematuria controls)


Point estimation (%) 95% CI Point estimation (%) 95% CI
Sensitivity 83.6 83.6 81.8 48.2, 97.7
Specificity 61.4 61.4 80.0 28.4, 99.5
ROC area 0.725 0.725 0.809 0.5, 1.0
+LR 2.1 2.1 4.0 1.2, 13.6
-LR 0.2 0.2 0.2 0.06, 0.8
DOR 8.0 8.0 18.0 1.5, 213
PPV 73.4 73.4 82.8 59.0, 94.1
NPV 74.6 74.6 78.9 51.4, 93.0

+LR, positive likelihood ratio; -LR, negative likelihood ratio; DOR, ROC area and diagnostic odds ratio; PPV, positive predictive value; NPV, negative predictive value