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. 2018 Mar 19;115(14):3686–3691. doi: 10.1073/pnas.1706096114

Table 1.

Study participant characteristics and comparison with the NHANES

Variables Study participant NHANES adult Standardized incidence ratio (55) 95% CI P value
Characteristics
 Age, y 4.43E-40*
  Median 55 26
  Range 20–98 0–80
 Sex 4.84E-04*
  Male 65.6% 49.2%
  Female 34.4% 50.8%
 Measured BMI
  Median (25–75%) 26 (23–29) 24.7 (20–30)
 Measured systolic blood pressure
  Median (25–75%) 123.5 (115–133) 116 (106–128)
 Measured LDL
  Median (25–75%) 114.5 (96–135) 103 (81–127)
Diseases
 Neoplasms
  Ever told you had cancer or malignancy 15.1% 9.5% 1.5 1.02–2.16 3.39E-02*
 Cardiovascular
  Ever told you had coronary heart disease 4.1% 4.0% 0.9 0.38–1.74 7.98E-01
 Chronic respiratory diseases
  Ever told you had COPD 1.0% 3.3% 0.2 0.02–0.88 9.52E-02
 Diabetes, urogenital, blood, and endocrine diseases
  Doctor told you have diabetes 4.6% 7.5% 0.3 0.13–0.54 9.63E-04*
 Cirrhosis and other chronic liver diseases
  Ever told you had any liver condition 6.1% 4.1% 1.1 0.55–1.89 7.75E-01
 Neurological disorders
  Blood relatives have Alzheimer’s disease 13.2% 13.3% 1.0 0.63–1.44 1.00E+00
Risk factors
 Alcohol use
  Had at least 12 alcoholic drinks per 1 y 90.0% 70.0% 1.2 0.99–1.37 2.76E-02*
 Tobacco smoking
  Smoked at least 100 cigarettes in life 38.4% 42.2% 0.8 0.58–0.97 8.90E-02
 High LDL cholesterol
  Now taking prescribed medicine 78.9% 85.4% 1.1 0.74–1.48 6.02E-01
 High blood pressure
  Ever told you had high blood pressure 23.0% 33.7% 0.5 0.38–0.69 6.81E-06*
  Taking prescription for hypertension 73.8% 83.6% 0.8 0.54–1.14 2.44E-01

The NHANES information is at https://www.cdc.gov/nchs/nhanes/. BMI, body mass index; COPD, chronic obstructive pulmonary disease.

*

P ≤ 0.05.