Table 2: Characteristics of Large-scale Systematic Community Atrial Fibrillation Screening Studies (>4,000 Individuals).

Study	Number of participants	Target population	Mean age (years)	Response rate (%)	Screening tool	Confirmation with 12-lead ECG	Total AF detected, n (%)	Previously undiagnosed AF detected, n (%)	Patients* indicated and given OAC, n (%)	NNS
Furberg et al. 1994[10]	5,151	Random sample of citizens from Medicare eligibility lists from four US communities	N/A (≥65)	57.6	12-lead ECG	N/A	277 (5.4)	77 (1.49)	N/A	67
Meschia et al. 2010[11]	29,861	Black Americans and residents of the southeastern ‘stroke belt region’ in the US	74.0 (median)	49.0	7- or 12-lead ECG	N/A	432 (1.4)	174 (0.58)	85 (48.9)	172
Schnabel et al. 2012[12]	5,000	Persons aged 35–74 from the city of Mainz and Mainz- Bingen region in Germany	52.2	60.4	12-lead ECG	N/A	161 (3.2)	25 (0.5)	N/A	200
Frewen et al. 2013[13]	4,890	Community dwelling citizens aged ≥50 years in the Republic of Ireland	63.8	37.1	3-lead ECG	No	118 (2.4)	45 (0.92)	N/A	109
Svennberg et al. 2015[14]	7,173	75–76-year-old population in Stockholm county or the Halland region in Sweden	N/A	53.8	1-lead ECG	No	884 (12.3) with history plus ECG	218 (3)	203 (93)	Single ECG: 200 Twice daily ECG for 2 weeks: 33
Chan et al. 2016[2]	13,122	Untargeted voluntary participation by Hong Kong citizens aged ≥18 years	64.7	N/A	1-lead ECG	No	239 (1.8)	101 (0.8)	N/A	129
Proietti et al. 2016[15]	65,747	Untargeted voluntary participation by Belgian citizens	58.0 (median)	N/A	1-lead ECG	Yes when 1-lead ECG unclear	911 (1.4)	603 (0.92)	N/A	109
Chan et al. 2017[16]	10,735	Untargeted voluntary participation by Hong Kong citizens aged ≥50 years	78.6	N/A	1-lead ECG	No	244 (2.3)	74 (0.69)	17 (24)	145

^*with previously undiagnosed AF. AF = atrial fibrillation; N/A = not applicable; NNS = number-needed-to-screen for one patient with newly diagnosed atrial fibrillation; OAC = oral anticoagulation.