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. 2018 Apr 7;24(13):1410–1418. doi: 10.3748/wjg.v24.i13.1410

Table 1.

Patients’ demographics and laboratory with n = 52 demonstrating autoimmune hepatitis-induced acute liver failure (9.2%)

Study population (n = 52) with AIH-induced ALF
Mean age (yr) 43.6 ± 14.9 (19-76)
Male 8 (15.4%)
Female 44 (84.6%)
Hepatic encephalopathy Grade I: 46/52 (88.4%)
Grade II: 2/52 (3.8%)
Grade III: 2/52 (3.8%)
Grade IV: 2/52 (3.8%)
Immunosuppressive therapy Steroid induction: 52/52 (100%)
Steroid maintenance: 30/52 (57.7%)
Steroid withdrawal: 20/52 (42.3%)
Azathioprine: 27/52 (51.9%)
Cyclosporine A: 7/52 (13.5%)
ALT (U/L) 1391.0 (843.5-2154.5)
Total bilirubin (mg/dL) 14.3 (11.7-18.7)
Creatinine (mg/dL) 0.76 (0.55-0.95)
INR 1.78 (1.64-2.00)
LabMELD-score 24 (22-26)
Immunoglobulin G (g/L) 17.2(13.1-22.8)
γ-globulin-fraction (%) 24.5 (19.5-29.3)

Data represents median and IQR. AIH: Autoimmune hepatitis; ALF: Acute liver failure; ALT: Alanine-aminotransferase.