Table 1.
Patients’ demographics and laboratory with n = 52 demonstrating autoimmune hepatitis-induced acute liver failure (9.2%)
| Study population (n = 52) with AIH-induced ALF | |
| Mean age (yr) | 43.6 ± 14.9 (19-76) |
| Male | 8 (15.4%) |
| Female | 44 (84.6%) |
| Hepatic encephalopathy | Grade I: 46/52 (88.4%) |
| Grade II: 2/52 (3.8%) | |
| Grade III: 2/52 (3.8%) | |
| Grade IV: 2/52 (3.8%) | |
| Immunosuppressive therapy | Steroid induction: 52/52 (100%) |
| Steroid maintenance: 30/52 (57.7%) | |
| Steroid withdrawal: 20/52 (42.3%) | |
| Azathioprine: 27/52 (51.9%) | |
| Cyclosporine A: 7/52 (13.5%) | |
| ALT (U/L) | 1391.0 (843.5-2154.5) |
| Total bilirubin (mg/dL) | 14.3 (11.7-18.7) |
| Creatinine (mg/dL) | 0.76 (0.55-0.95) |
| INR | 1.78 (1.64-2.00) |
| LabMELD-score | 24 (22-26) |
| Immunoglobulin G (g/L) | 17.2(13.1-22.8) |
| γ-globulin-fraction (%) | 24.5 (19.5-29.3) |
Data represents median and IQR. AIH: Autoimmune hepatitis; ALF: Acute liver failure; ALT: Alanine-aminotransferase.