Table 3.
Performance of endoscopic and histological findings for Helicobacter pylori infection
| Accuracy | Sensitivity | Specificity | PPV | NPV | |
| Endoscopic findings | |||||
| Kyoto classification of gastritis1 | 89.7 | 78.3 | 92.0 | 66.7 | 95.4 |
| Atrophy2 | 85.3 | 82.6 | 85.8 | 54.3 | 96.0 |
| Intestinal metaplasia | 86.0 | 39.1 | 95.6 | 64.3 | 88.5 |
| Enlarged folds | 85.3 | 17.4 | 99.1 | 80.0 | 85.5 |
| Nodularity | 84.6 | 8.7 | 100 | 100 | 84.3 |
| Redness | 86.8 | 52.2 | 93.8 | 63.2 | 90.6 |
| Gastric sticky mucus | 78.7 | 34.8 | 87.6 | 36.4 | 86.8 |
| Gastric ulcer | 83.8 | 4.3 | 100 | 50.0 | 83.7 |
| Duodenal ulcer | 82.4 | 4.3 | 98.2 | 33.3 | 83.5 |
| Gastroesophageal reflux disease | 71.3 | 8.7 | 84.1 | 10.0 | 81.9 |
| Hiatal hernia | 72.8 | 8.7 | 85.8 | 11.1 | 82.2 |
| Fundic gland polyp | 54.4 | 4.3 | 64.6 | 2.4 | 76.8 |
| Histological findings | |||||
| H. pylori density | 96.3 | 78.3 | 100 | 100 | 95.8 |
| Chronic inflammation | 80.1 | 91.3 | 77.9 | 45.7 | 97.8 |
| Neutrophil activity | 94.1 | 65.2 | 100 | 100 | 93.4 |
| Intestinal metaplasia | 81.6 | 4.3 | 97.3 | 25.0 | 83.3 |
| Glandular atrophy | 81.6 | 4.3 | 97.3 | 25.0 | 83.3 |
1
A score of 2 or more was defined as positive;
2
A score of 1 or more was defined as positive. The data are presented as %. Positive urea breath test was defined as H. pylori infection. PPV: Positive predictive value; NPV: Negative predictive value; H. pylori: Helicobacter pylori.