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. 2018 Mar 25;2018:1538632. doi: 10.1155/2018/1538632

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Copyright © 2018 Xueli Cao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of compound 9 on the replicative lifespan of uth1 (a), skn7 (b), sod1 (c), and sod2 (d) mutants. The average lifespan of K6001 in the control group was 7.93 ± 0.41; Res at 10 μM, 10.45 ± 0.52^∗∗∗; and compound 9 at 3 μM, 10.33 ± 0.49^∗∗. (a) The average lifespan of Δuth1 in the control group was 11.60 ± 0.51 and compound 9 at 3 μM, 10.95 ± 0.46. (b) The average lifespan of Δskn7 in the control group was 9.88 ± 0.41 and compound 9 at 3 μM, 10.40 ± 0.53. (c) The average lifespan of Δsod1 in the control group was 6.55 ± 0.32 and compound 9 at 3 μM, 6.65 ± 0.34. (d) The average lifespan of Δsod2 in the control group was 6.28 ± 0.25 and compound 9 at 3 μM, 6.50 ± 0.25 (^∗∗P < 0.01 and ^∗∗∗P < 0.001).