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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Anal Bioanal Chem. 2018 Mar 14;410(12):3025–3035. doi: 10.1007/s00216-018-0985-y

Figure 1.

Figure 1

Schematic showing the process of creating an insert-based microfluidic device for 3D cell culture that can be easily scaled and multiplexed. Fibers are directly electro/blow-spun onto a polystyrene film and subsequently laser-cut into inserts. The fused edges aid in fiber adherence on the polystyrene film. After cells are seeded on the fibrous scaffolds, they can be easily assembled in a 3D-printed fluidic vessel that can be connected to downstream analytical modules.