Table 1.
Clinical characteristics of patients with BP according to mucosal involvement.
| All BP patients | Patients without mucosal involvement | Patients with mucosal involvement | Pvalue | |
|---|---|---|---|---|
| Number of patients (n) | 95 | 77 | 18 | NA |
| Sex ratio (F/M) | 1.88 | 1.96 | 1.57 | 0.68 |
| Age, mean ± SD | 81.7 ± 9.3 | 82.4 ± 8.9 | 78.7 ± 10.6 | 0.18 |
| Patients with at least 10 daily new blisters,a n (%) | 45 (47.4) | 32 (41.6) | 13 (72.2) | 0.02 |
| Number of daily new blisters,a mean ± SD | 19.3 ± 29.8 | 17.6 ± 27.1 | 26.5 ± 39.4 | 0.07 |
| BPDAI global score, mean ± SD | 39.6 ± 27 | 35.8 ± 25.1 | 56.1 ± 29.2 | 0.008 |
| Activity of total skin involvement, mean ± SD | 38.1 ± 26 | 35.1 ± 25 | 51.0 ± 26.8 | 0.021 |
| Blisters/erosions, mean ± SD | 24.9 ± 17.6 | 22.1 ± 16.4 | 36.9 ± 17.6 | 0.001 |
| Erythema/urticaria, mean ± SD | 13.2 ± 13.6 | 13 ± 13.3 | 14.1 ± 15.1 | 0.91 |
| Activity of mucosal involvement, mean ± SD | 0.8 ± 2.4 | 0 | 4.0 ± 4.2 | NA |
| Damage, mean ± SD | 0.8 ± 2 | 0.7 ± 1.8 | 1.1 ± 2.6 | 0.78 |
| Patients with severe disease according BPDAI,b n (%) | 24 (25) | 16 (20.8) | 8 (44.4) | 0.04 |
Subsets of BP patients with or without mucosal involvement were compared and P-value was obtained using Chi2 tests for comparison between qualitative variables and nonparametric, Mann–Whitney tests for comparison between quantitative values.
aDetermined over a 3-day period.
bDetermined by BPDAI global score ≥56.
NA, not applicable; BP, bullous pemphigoid; BPDAI, BP Disease Area Index.