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. 2018 Apr 9;8:5681. doi: 10.1038/s41598-018-23830-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Lung histopathology in B. pseudohinzii-infected mice. (a–d) H&E-stained paraffin section; (c) and (b) represent higher magnifications of boxed areas in (b) and (a), respectively, demonstrating BALT aggregates; additional BALT is indicated by arrows in (a). The lung section depicted in a–c is taken from an animal which was also positive for Pasteurella pneumotropica. (d) Interstitial pneumonia with neutrophils (arrow). (e) The incidence of neutrophils is significantly elevated in the BAL fluid from B. pseudohinzii-positive (pos; n = 6) compared to B. pseudohinzii-negative mice (neg; n = 6) (mean ± SEM; Student’s unpaired t-test).