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. 2018 Apr 9;8:5685. doi: 10.1038/s41598-018-24134-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Lead content in whole blood (A) and femur (B) in mice. Male KM mice were given no lead (group 1), lead acetate + Lpp-OmpA displayed E. coli (group 2), saturatedly leaded PbrR-displayed E. coli (group 3), and unsaturatedly leaded PbrR-displayed E. coli (group 4), in a dose of about 20 μg lead/mouse daily. Blood and femur were harvested on day 15, and lead concentrations were determined. Each circle represents one sample (n = 9), and the bars indicated the mean values. *A significant difference (One-way ANOVA statistical analysis, P < 0.001) when compared to group 2, while there is no significant difference between group 1 and group 4.