Table 1.
Observational data on cure.
| Treatment length | RpZHE | RZME | RZMH |
|---|---|---|---|
| 2 months | 0/3 | 0/3a | 0/3 |
| 2.5 months | 1/3 | 0/3 | 0/3 |
| 3 months | 2/3 | 3/3 | 0/3 |
| 3.5 months | 2/3 | 2/3 | 0/3 |
| 4 months | 3/3 | 2/2b | 1/3 |
| 4.5 months | 2/2c | 3/3 | 2/3 |
| 5 months | 3/3 | 3/3 | 3/3 |
| 5.5 months | 3/3 | 2/2b | 3/3 |
| 6 months | 3/3 | 3/3 | 3/4d |
a0/3 = 0 of 3 mice was cured (culture-negative lungs 3 months post-treatment) after indicated treatment duration; bAnimal died of a non-tuberculosis cause prior to time point; cThe plates for colony counting were contaminated and no counting could be performed; dThe backup mouse included for the RZMH regimen was still alive at the 6 month time point. R = rifampicin, Rp = rifapentine, Z = pyrazinamide, M = moxifloxacin, H = isoniazid, E = Ethambutol.