Table 2.

Evaluation of cell-type specific reference gene expression in ABCA7 expression model. The neuronal reference gene was synaptophysin while the microglial reference was the geometric mean of ITGAM and AIF1 expression. The model with both cell types used the geometric mean of synaptophysin and the microglial geometric mean.

Reference Gene Type	Adjusted R2	AD Beta Coefficient (p value)	Rs3764650 Beta Coefficient (p value)	Reference Gene Beta Coefficient (p value)
Neuronal	0.700	0.322 (1.7×10−4)	−0.236 (0.003)	0.840 (7.1×10−15)
Microglial	0.323	0.240 (0.050)	−0.257 (0.029)	0.556 (1.6×10−5)
Both Cell Type	0.697	0.337 (3.9×10−4)	−0.234 (0.008)	0.805 (1.6×10−12)