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. 2018 Apr 9;25:32. doi: 10.1186/s12929-018-0435-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of avicequinone B on anchorage-independent growth. a Colony formation of single-cell H460 cells was evaluated under a microscope after culture in soft agar for 14 days. b Relative colony number and c relative colony size were gradually decreased incubation of single-cell H460 with 1–4 μM of avicequinone B. Data represent the means ± SD (n = 3). *p ≤ 0.05 versus untreated control cells