Table 3.
Crude onchocerciasis MF prevalence and density in Sierra Leone after five annual rounds of MDA
| Baseline survey | 2010 Epidemiological Evaluation | Percentage reduction (%) | Significance test (P-values) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. examined | MF prev (%) | AMD-all (mf/snip) | AMD-positive (mf/snip) | No. examined | MF prevalence (95% CI) |
AMD-all (mf/snip) (95% CI) |
AMD-positive (mf/snip) (95% CI) |
MF prev | AMD-all | AMD-positive | MF prev | AMD-all | AMD-positive | |
| Overall | 7116 | 53.09 | 15.33 | 28.87 | 5621 | 21.12 (20.07–22.20) | 1.75 (1.48–2.02) | 8.29 (7.07–9.50) | 60.22 | 88.58 | 71.29 | 0 | 0 | 0 |
| By district | ||||||||||||||
| Bo | 1499 | 54.3 | 18.91 | 34.82 | 1079 | 25.77 (23.24–28.46) | 2.95 (2.11–3.80) | 11.46 (8.40–14.53) | 52.55 | 84.4 | 67.09 | 0 | 0 | 0 |
| Bombali | 368 | 57.88 | 16.85 | 29.1 | 494 | 16.19 (13.21–19.70) | 1.58 (0.86–2.29) | 9.72 (5.71–13.72) | 72.02 | 90.62 | 66.6 | 0 | 0 | 0 |
| Bonthe | 180 | 40.56 | 7 | 17.25 | 165 | 26.67 (20.51–33.16) | 3.05 (0.41–5.68) | 11.42 (1.71–21.13) | 34.25 | 56.43 | 33.8 | 0.009 | 0.004 | 0.247 |
| Kailahun | 183 | 49.73 | 12.06 | 24.25 | 118 | 23.73 (16.96–32.16) | 2.01 (0.47–3.55) | 8.46 (2.31–14.62) | 52.28 | 83.33 | 65.11 | 0 | 0 | 0 |
| Kambia | 155 | 61.94 | 17.8 | 28.73 | 98 | 23.47 (16.18–32.76) | 1.04 (0.43–1.65) | 4.41 (2.24–6.58) | 62.11 | 94.16 | 84.65 | 0 | 0 | 0 |
| Kenema | 286 | 45.12 | 6.51 | 14.42 | 101 | 20.79 (14.02–29.70) | 1.35 (0.18–2.51) | 6.48 (1.09–11.86) | 53.9 | 79.26 | 55.06 | 0 | 0 | 0.217 |
| Koinadugu | 168 | 58.33 | 18.38 | 31.51 | 58 | 6.90 (2.71–16.43) | 0.05 (0.00–0.11) | 0.75 (0.00–1.55) | 88.18 | 99.73 | 97.62 | 0 | 0 | 0.005 |
| Kono | 1105 | 39.01 | 14.63 | 37.48 | 521 | 9.02 (6.85–11.79) | 0.32 (0.18–0.46) | 3.53 (2.31–4.75) | 76.87 | 97.81 | 90.58 | 0 | 0 | 0 |
| Moyamba | 1055 | 58.2 | 12.06 | 20.74 | 988 | 29.96 (27.19–32.89) | 1.64 (1.27–2.01) | 5.46 (4.35–6.58) | 48.52 | 86.4 | 73.67 | 0 | 0 | 0 |
| Port Loko | 653 | 57.12 | 13.83 | 24.21 | 738 | 26.02 (22.98–29.30) | 3.10 (1.80–4.40) | 11.91 (7.12–16.71) | 54.45 | 77.58 | 50.81 | 0 | 0 | 0 |
| Pujehun | 560 | 53.57 | 9.84 | 18.36 | 348 | 7.76 (5.39–11.03) | 0.60 (0.06–1.14) | 7.76 (1.03–14.49) | 85.52 | 93.9 | 57.73 | 0 | 0 | 0.002 |
| Tonkolili | 904 | 60.4 | 22.09 | 36.5 | 913 | 16.10 (13.86–18.63) | 0.67 (0.43–0.91) | 4.16 (2.81–5.50) | 73.34 | 96.97 | 88.6 | 0 | 0 | 0 |
| By sex | ||||||||||||||
| Male | 3461 | 55.19 | 21.11 | 38.16 | 2805 | 24.49 (22.94–26.12) | 2.55 (2.04–3.06) | 10.40 (8.43–12.36) | 54.24 | 87.92 | 72.75 | 0 | 0 | 0 |
| Female | 3655 | 51.11 | 9.94 | 19.38 | 2816 | 17.76 (16.39–19.21) | 0.96 (0.77–1.15) | 5.40 (4.40–6.40) | 64.12 | 90.34 | 72.14 | 0 | 0 | 0 |
| Age groups | ||||||||||||||
| 1–9 | 2182 | 11.05 | 0.91 | 8.24 | 1930 | 1.71 (1.22–2.39) | 0.04 (0.02–0.06) | 2.47 (1.49–3.45) | 82.55 | 95.6 | 70.02 | 0 | 0.168 | 0.02 |
| 10–19 | 1317 | 50.57 | 6.91 | 13.67 | 889 | 16.09 (13.82–18.65) | 0.80 (0.51–1.08) | 4.94 (3.31–6.58) | 66.4 | 88.42 | 63.86 | 0 | 0 | 0 |
| 20–29 | 780 | 78.21 | 19.94 | 25.5 | 648 | 38.27 (34.61–42.07) | 3.68 (2.48–4.88) | 9.58 (6.58–12.58) | 49.09 | 81.54 | 62.43 | 0 | 0 | 0 |
| 30–39 | 824 | 80.95 | 28.88 | 35.64 | 624 | 37.18 (33.48–41.04) | 3.49 (2.34–4.64) | 9.38 (6.43–12.33) | 52.41 | 87.92 | 73.68 | 0 | 0 | 0 |
| 40–49 | 735 | 82.31 | 35.94 | 43.66 | 542 | 38.75 (34.74–42.91) | 4.09 (2.65–5.54) | 10.56 (6.99–14.13) | 51.2 | 88.62 | 75.81 | 0 | 0 | 0 |
| 50–59 | 575 | 81.39 | 30.37 | 37.31 | 416 | 37.02 (32.52–41.76) | 2.61 (1.15–4.06) | 7.04 (3.18–10.89) | 52.55 | 91.41 | 81.13 | 0 | 0 | 0 |
| ≥ 60 | 684 | 76.17 | 21.58 | 28.34 | 566 | 29.33 (25.73–33.21) | 2.10 (1.47–2.73) | 7.17 (5.22–9.12) | 59.74 | 90.27 | 74.7 | 0 | 0 | 0 |