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Significant effect of clinical group on stress-induced [11C]-(+)-PHNO displacement in the substantia nigra (SN) (F = 6.896, df = 2,54, P = .002) and the whole striatum (F = 4.362, df = 2,54, P = .018), including associative striatum (AST) (F = 6.131, df = 1,54, P = .004), sensorimotor striatum (SMST) (F = 3.384, df = 2,54, P = .041), but not in the limbic striatum (LST) (F = 0.173, df = 2, 54, P = .842). HV, healthy volunteer; CHR, clinical high risk; SCZ, schizophrenia.
