. 2016 Nov 4;24(5-6):136–147. doi: 10.1177/2040206616671571

Table 5.

Sensitivity to oxoglaucine in plaque inhibition tests of virus brain isolates from newborn mice infected with CVB1.

Group	Oxoglaucine IC₅₀ values (μM) of viral brain samples
	Taken on day (after viral inoculation)
	4	5	6	7	8	9	10	11	12	13
Placebo	0.411	0.743	^a	^a	^a	^a	^a	^a	^a	^a
Oxoglaucine 25 mg/kg	1.198	1.048	^a	^a	^a	^a	^a	^a	^a	^a
P₂₅M₇₅O₂₅ consecutive	0.914	0.979	0.851	0.727	0.299	0.396	0.287	0.299	0.221	0.153^###
P₂₅M₇₅O₂₅ simultaneous	1.196	1.817	^a	^a	^a	^a	^a	^a	^a	^a

After day 5, no animals were alive, 100% mortality rate. Statistical analysis was performed with one-way ANOVA (Bonferroni’s multiple comparison post-test).

^###

P < 0.001 vs. PMO consecutive day 5.