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Binding of Fc-μTP-L309C to Fc receptor. (A) Biacore analysis of binding of Fc-μTP-L309C to FcγR components CD16a, CD32a, CD32b/c, and CD64. Affinity of monomeric Fc to CD16 was too low to generate a signal. (B) Binding of Fc-μTP-L309C and IVIG to primary human monocytes and granulocytes. Data shown as mean + SEM, n = 3 individual experiments using cells from three different donors.
