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. 2017 Dec 23;77(4):523–532. doi: 10.1136/annrheumdis-2017-212127

Figure 3.

Figure 3

ACR and PASI response rates by treatment group (PD-PPS). (A–C) ACR response rates (%, with 95% CI) and (D-E) PASI response rates (%, with 95% CI). Dashed vertical lines indicate drug intake (weeks 0, 3 and 6). Note: top three doses of bimekizumab (160 mg/80 mg/80 mg, 240 mg/160 mg/160 mg, 560 mg/320 mg/320 mg); PASI75 and PASI100 were only calculated for patients with BSA ≥3% psoriasis involvement at baseline. Modifications in concomitant therapy were permitted post week 8. Subject 003–00320 was excluded from the analyses for all time points after week 8 due to receiving an increased dose of naproxen, adalimumab and leflunomide for control of worsening disease. ACR20, American College of Rheumatology 20% response criteria; ACR50, American College of Rheumatology 50% response criteria; ACR70, American College of Rheumatology 70% response criteria; PASI75, Psoriasis Area and Severity Index 75% response criteria; PASI100, Psoriasis Area and Severity Index 100% response criteria; PD-PPS, pharmacodynamic per-protocol set.