Skip to main content
editorial
. 2017 Oct 27;104(8):632–633. doi: 10.1136/heartjnl-2017-312269

Table 1.

99th centile=the upper reference limit as determined in a healthy reference range population

99th centile
(Diagnostic threshold)		 10% coefficient of variation* Limit of detection
Roche Elecsys high-sensitivity cardiac troponin T7 14 ng/L 13 ng/L 5 ng/L
Abbott ARCHITECTSTAT high-sensitivity cardiac troponin I8 16 ng/L (females)
34 ng/L (males)
26 ng/L (single threshold)		 4.7 ng/L 2 ng/L

Limit of detection, the lowest concentration which can be reliably distinguished from a sample with no troponin present.

*Lowest concentration where coefficient of variation is <10% (measure of dispersion of replicate sample results around the mean (SD/mean)).