Table 3.
Cytological cure compared with day 0 by treatment strategy and time of examination
Day of examination and bacteriological status at day 0 | Treatment strategy | |||||
Individualised homeopathy (n=60) | Placebo (n=60) | Antibiotic (n=60) | ||||
n/n | % | n/n | % | n/n | % | |
Day 7 | ||||||
Positive (n=120) | ||||||
SCC<100,000 cells/ml | 0/40 | 0.0 | 1/38 | 2.6 | 1/41* | 2.4 |
SCC was lower | 18/40 | 45.0 | 20/38 | 52.6 | 34/41 | 82.9 |
SCC was higher | 7/40 | 17.5 | 0/38 | 0.0 | 3/41 | 7.3 |
Non-responders | 15/40 | 37.5 | 17/38 | 44.7 | 3/41 | 7.3 |
Negative (n=60) | ||||||
SCC<100,000 cells/ml | 2/20 | 10.0 | 6/22 | 27.3 | 3/18 | 16.7 |
SCC was lower | 13/20 | 65.0 | 13/22 | 59.1 | 13/18 | 72.2 |
SCC was higher | 4/20 | 20.0 | 3/22 | 13.6 | 2/18 | 11.1 |
Non-responders | 1/20 | 5.0 | 0/22 | 0.0 | 0/18 | 0.0 |
Day 14 | ||||||
Positive (n=120) | ||||||
SCC<100,000 cells/ml | 3/40 | 7.5 | 1/38 | 2.6 | 7/42 | 16.7 |
SCC was lower | 13/40 | 32.5 | 15/38 | 39.5 | 23/42 | 54.8 |
SCC was higher | 3/40 | 7.5 | 2/38 | 5.3 | 2/42 | 4.8 |
Non-responders | 21/40 | 52.5 | 20/38 | 52.6 | 10/42 | 23.8 |
Negative (n=60) | ||||||
SCC<100,000 cells/ml | 5/20 | 25.0 | 6/22 | 27.3 | 7/18 | 38.9 |
SCC was lower | 12/20 | 60.0 | 8/22 | 36.4 | 8/18 | 44.4 |
SCC was higher | 0/20 | 0.0 | 4/22 | 18.2 | 1/18 | 5.6 |
Non-responders | 3/20 | 15.0 | 4/22 | 18.2 | 2/18 | 11.1 |
Day 28 | ||||||
Positive (n=120) | ||||||
SCC<100,000 cells/ml | 2/39† | 5.1 | 5/38 | 13.2 | 9/42 | 21.4 |
SCC was lower | 13/39 | 33.3 | 11/38 | 28.9 | 17/42 | 40.5 |
SCC was higher | 0/39 | 0.0 | 1/38 | 2.6 | 1/42 | 2.4 |
Non-responders | 24/39 | 61.5 | 21/38 | 55.3 | 15/42 | 35.7 |
Negative (n=60) | ||||||
SCC<100,000 cells/ml | 6/19† | 31.6 | 8/22 | 36.4 | 7/17† | 41.2 |
SCC was lower | 7/19 | 36.8 | 5/22 | 22.7 | 6/17 | 35.3 |
SCC was higher | 2/19 | 10.5 | 3/22 | 13.6 | 0/17 | 0.0 |
Non-responders | 4/19 | 21.1 | 6/22 | 27.3 | 4/17 | 23.5 |
Results are given in number of total cures out of cases treated (n/n) and in % of all cases treated.
*Low quantity of milk: SCC measurement was not possible.
†Early culling of one cow due to different reasons (dangerous handling, lameness, fertility disorder).
Non-responders, cows with no clinical cure were rated as non-responsive to the treatment given; SCC, somatic cell count.