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. 2017 Oct 6;73(1):57–65. doi: 10.1093/jac/dkx342

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© The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — (a) The imperfect DRs (underlined, with lower-case letters denoting the bases that differ) flanking ICEApl2 share sequence identity with 14 bases found in prfC genes (b) from A. pleuropneumoniae (e.g. accession number CUU51349) and Vibrio species (e.g. accession number KU341408). (c) The closed circular form of ICEApl2 shows that the junction (attP sequence, underlined) formed by cross-over between the repeats retains a 14 bp sequence differing only at one base from the A. pleuropneumoniae prfC gene. Sequences in the closed and dashed boxes indicate the 5′ and 3′ ends, respectively, of the ICEApl2 sequence.