Table III.

Average detection times of THC, metabolites and individual ranges in blood and oral fluid following oral consumption of cannabis brownies

THC dose (mg)	Blood THCCOOH ELISA (h) (cutoff = 10 ng/mL	Blood THC LC–MS-MS (h) (LOQ = 0.5 ng/mL)	Blood 11-OH-THC LC–MS-MS (h) (LOQ = 0.5 ng/mL)	Blood THCCOOH LC–MS-MS (h) (LOQ = 0.5 ng/mL)	Oral fluid THC ELISA (h) (cutoff = 4 ng/mL)	Oral fluid THCCOOH ELISA (h) (cutoff = 4 ng/mL)	Oral fluid THC LC–MS-MS (h) (LOQ = 1 ng/mL)	Oral fluid THCCOOH LC–MS-MS (h) (cutoff = 0.050 ng/mL)
Detection time (h) to first positive, mean (range)
10	1.5 (1.0–2.0)	1.1 (1.0–1.5)	1.4 (1.0–3.0)	1.7 (1.0–3.0)	0.17 (0.2–0.2)	0.17 (0.2–0.2)	0.17 (0.2–0.2)	3.0 (3.0–3.0)
25	0.8 (0.5–1.0)	1.1 (0.5–2.0)	1.1 (0.5–2.0)	1.1 (0.5–2.0)	0.23 (0.2–0.5)	0.23 (0.2–0.5)	0.23 (0.2–0.5)	3.6 (0.2–8.0)
50	0.9 (0.5–1.0)	0.8 (0.5–1.0)	0.9 (0.5–1.0)	0.8 (0.5–1.0)	0.17 (0.2–0.2)	0.17 (0.2–0.2)	0.17 (0.2–0.2)	1.6 (0.2–4.0)
Detection time (h) to last positive, mean (range)
10	30.3 (8–54)	2.0 (0–5)	2.6 (0–4)	6.7 (3–12)	1.5 (1,2)	0.7 (0–2)	1.9 (2,3)	1.0 (0–3)
25	50.0 (34–74)	7.8 (4–22)	5.5 (3–8)	24.0 (8–46)	2.3 (1–4)	16.4 (1–50)	3.0 (2–6)	26.3 (0–70)
50	66.7 (22–122)	6.8 (3–12)	7.7 (4–12)	51.3 (6–94)	10.0 (2–22)	25.2 (3–70)	9.5 (3–22)	37.3 (0–78)