Fig. 7.

Dietary source alters miRNA expression in LPS-stimulated splenocytes from MRL/lpr mice. (A, B) Taqman miRNA assays were performed to quantify lupus-associated miRNA expression in splenocytes. (A) miRNA expression in non-stimulated splenocytes. (B) miRNA expression in splenocytes after 24 h of 500 ng ml⁻¹ LPS stimulation. Expression is shown as relative expression level to mice fed the RD diet. (C–H) miRNA expression in splenocytes without stimulation (T0) and after 24 h of LPS stimulation (LPS). Data are expressed relative to the non-stimulated mean. The graphs represent mean + SEMs (n = 4 mice per group). *P < 0.05, **P < 0.01, ***P < 0.001, (A, B) one-way ANOVA, (C–H) t-test.