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. Author manuscript; available in PMC: 2018 Apr 9.
Published in final edited form as: Compr Physiol. 2017 Jun 18;7(3):891–944. doi: 10.1002/cphy.c160033

Figure 17.

Figure 17

Schematic representation of the dystrophin associated protein complex in muscle. The three subcomplexes are shown: the dystroglycan subcomplex (blue), the dystrobrevin:syntrophin subcomplex (red) and the sarcoglycan:sarcospan subcomplex (green). Also indicated are the muscular dystrophies caused due to defects or deficiencies of proteins within the dystrophin associated protein complex. Abbreviations: BMD, Becker muscular dystrophy; CMD1C-1D, congenital muscular dystrophy type 1C-1D; DMD, Duchenne muscular dystrophy; FCMD, Fukuyama; CMD, LGMD2C-2F, limb-girdle muscular dystrophy type 2C-2F; LAMA2, laminin alpha 2 chain or merosin-deficient muscular dystrophy; MEB, muscle-eye-brain disease; WWS, Walker–Warburg syndrome. [Fig. reprinted, with permission, from (583).]