Table 3. Temporal development of lung volume and air trapping over 24 months.
| Lung | Baseline | 3 month | 12 month | 24 month | p | |
|---|---|---|---|---|---|---|
| Volume [cm3] | ||||||
| B30f Insp. | manually | 3653.26 ±909.92 |
3643.03 ±1014.31 |
3973.5 ±1184.7 |
4440.41 ±1238.32 |
<0.0001 |
| automatic | 3650.87 ±908.89 |
3641.38 ±1011.11 |
3969.99 ±1181.85 |
4435.17 ±1236.43 |
<0.0001 | |
| B60f Insp. | manually | 3608.79 ±896.88 |
3643.03 ±1014.31 |
3972.8 ±1184.55 |
4505.61 ±1253.03 |
<0.0001 |
| automatic | 3597.88 ±892.34 |
3641.38 ±1011.11 |
3968.75 ±1180.54 |
4495.61 ±1249.2 |
<0.0001 | |
| B30f Exp. | manually | 1259.34 ±374.04 |
1310.39 ±512.75 |
1430.32 ±476.48 |
1615.05 ±509.09 |
<0.0003 |
| automatic | 1194.94 ±396.65 |
1264.71 ±540.25 |
1396.96 ±487.09 |
1584.57 ±533.53 |
<0.0002 | |
| B60f Exp. | manually | 1265.22 ±376.85 |
1310.39 ±512.75 |
1429.99 ±493.21 |
1615.05 ±509.09 |
<0.0004 |
| automatic | 1228.59 ±376.63 |
1296.5 ±522.06 |
1386.8 ±478.32 |
1598.22 ±525.09 |
<0.0003 | |
| Air trapping (E/I MLA) | ||||||
| B30f | manually | 0.63±0.1 | 0.64±0.1 | 0.65±0.09 | 0.67±0.08 | 0.59 |
| automatic | 0.65±0.09 | 0.66±0.09 | 0.66±0.08 | 0.68±0.07 | 0.74 | |
| B60f | manually | 0.62±0.1 | 0.63±0.1 | 0.64±0.09 | 0.66±0.08 | 0.59 |
| automatic | 0.64±0.09 | 0.64±0.09 | 0.66±0.09 | 0.67±0.08 | 0.50 | |
Mean and standard deviation for total lung volume [cm3] and air trapping, calculated for fully automatic and manually corrected segmentations at baseline 3, 12 and 24 months. Total lung volume and air trapping increased steadily over time. Changes were significant for volume changes but not significant for air trapping.