Table 2. IVF/ICSI-characteristics and outcomes in matched fresh and deferred frozen embryo transfer groups.
Fresh-ET group (n = 135) | Def-ET group (n = 135) | p-value | |
---|---|---|---|
Number of oocytes retrieved (mean ± SD) | 7.4 ± 4.3 | 9.9 ± 7.0 | 0.001 pt |
Total number of embryos transferred | 278 | 224 | NA |
Mean No. of embryos transferred (mean ± SD) | 2.1 ± 0.9 | 1.7 ± 0.9 | <0.001 pt |
Total number of embryo transfers | 155 | 170 | NA |
Mean No. of transfers (mean ± SD) | 1.2 ± 0.4 | 1.3 ± 0.7 | 0.132 pt |
Cumulative clinical pregnancy rate—(n,%) | 40 (29.6) | 58 (43.0) | 0.047 mn |
Miscarriage—(n,%) | 16/40 (40.0) | 11/58 (19.0) | 0.022 k |
Multiple pregnancy—(n,%) | 7/40 (17.5) | 5/58 (8.6) | 0.220 k |
Cumulative ongoing pregnancy—(n,%) | 24 (17.8) | 47 (34.8) | 0.005 mn |
Cumulative live birth rate a—(n,%) | 21 (15.6) | 41 (29.6) | 0.012 mn |
IVF/ICSI, in vitro fertilization / intra cytoplasmic sperm injection; Fresh-ET, Fresh embryo transfer; Def-ET, Deferred frozen- thawed embryo transfer; NA, non applicable
pt, Paired t-test;
mn, McNemar test;
k Pearson’s chi-square test.
a 2 and 5 women were lost to follow up in Fresh and Def-ET group respectively