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. 2018 Apr 9;13(4):e0195305. doi: 10.1371/journal.pone.0195305

Table 1. Characteristics of the study population.

Characteristic Exposed area Reference area
Inflammatory bowel disease Low back pain Inflammatory bowel disease Low back pain
Patients, n 141 6,127 109 4,342
Gender (female) 54% 51% 48% 52%
Age, in years, mean (±SD) 50 (±17) 51 (±18)*** 49 (±20) 50 (±19)
    3–24, n (%) 11 (8%) 651 (11%) 20 (18%) 494 (11%)
    25–44, n (%) 41 (29%) 1,406 (23%) 19 (17%) 1,126 (26%)
    45–64, n (%) 58 (41%) 2,522 (41%) 41 (38%) 1,720 (40%)
    ≥65–104, n (%) 31 (22%) 1,548 (25%)*** 29 (27%) 1,002 (23%)
Healthcare utilisation
Total number of presented morbidity with GP in the reporting year and three previous years to the diagnosis, mean (±SD) 31 (±32) 29 (±31)*** 38 (±42) 34 (±39)
Total number of drug prescriptions in the reporting year and three previous years to the diagnosis, mean (±SD) 43 (±65) 32 (±57)** 46 (±78) 34 (±55)
Exposure to livestock
Patients, n 135 5,790 N/A N/A
Distance to nearest livestock farm, n (%) N/A N/A
≤500m 64 (47%) 3,165 (55%)
>500m 71 (53%) 2,625 (45%)
Number of livestock farms
≤500m, n (%)
0 72 (53%) 2,663 (46%)
1–2 32 (24%) 1,810 (31%)
3 > 13 30 (22%) 1,314 (23%)
Presence of farm animals
≤500m (yes or no), n (%)
Pigs 33 (24%) 1,508 (26%)
Poultry 22 (16%) 642 (11%)
Cattle 43 (32%) 2,465 (43%)
Others (goats, sheep
and minks)
25 (19%) 657 (11%)

** p-value < 0.01

*** p-value = 0.001, ref are patients in the reference area