Table 2. Antigenic characterization of wild-type and selected H1N1 influenza viruses by hemagglutination inhibition and microneutralization assays.
| H1N1 virus | Titer | |||||||
|---|---|---|---|---|---|---|---|---|
| Goat antiserum against CA/04 | Ferret antiserum against: | MAbs against CA/04: | ||||||
| CA/04 | A/CA/07/09 | A/TN/1-560/09 | 28665 | 28666 | 28667 | 28668 | ||
| CA/04 | 1280a | 1280 | 1280 | 1280 | 6400a/6400b | 51200/>204800 | 800/6400 | 12800/102400 |
| CA/04+MAA | 160 | 10 | 80 | 10 | <200/<200 | 51200/>204800 | 400/6400 | <50/<200 |
| CA/04+SNA | 160 | 10 | 160 | 10 | <200/<200 | 51200/>204800 | 400/3200 | 50/200 |
| CA/04+Calu-3 | 1280 | 1280 | 1280 | 1280 | 1600/6400 | 51200/>204800 | 400/3200 | 12800/51200 |
a Values are expressed as reciprocals of serum/antibody dilutions that inhibited 8 hemagglutination units of H1N1 influenza virus.
b Neutralizing antibody titers (arithmetic mean) to H1N1 viruses were titrated in MDCK cells.