Figure 1.

Adjusted estimated survival curves in patients with or without disseminated intravascular coagulation (DIC). A, DIC was diagnosed on the basis of the International Society on Thrombosis and Haemostasis (ISTH) criteria for overt DIC. Significant associations between anticoagulant therapy and lower in‐hospital mortality rates were observed only in patients with DIC (adjusted hazard ratio [HR], 0.609; 95% confidence interval [CI], 0.456–0.814; P = 0.001), whereas mortality rates in patients without DIC were not different regardless of anticoagulant therapy (adjusted HR, 0.941; 95% CI, 0.773–1.145; P = 0.543). B, DIC was diagnosed on the basis of the Japanese Association for Acute Medicine (JAAM) DIC criteria. Significant associations between anticoagulant therapy and lower in‐hospital mortality rates were observed only in patients with DIC (adjusted HR, 0.685; 95% CI, 0.559–0.839; P < 0.001), whereas mortality rates in patients without DIC were not different regardless of anticoagulant therapy (adjusted HR, 1.104; 95% CI, 0.839–1.453; P = 0.478). Dotted line, patients in the control group; solid line, patients in the anticoagulant group. Cited as Figure 3 in our previous report.19