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. 2018 Feb 14;36(11):1073–1079. doi: 10.1200/JCO.2017.76.5719

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Fig 2. — Disease-free survival (DFS), breast cancer–free interval (BCFI), and overall survival (OS) for patients with (A-C) estrogen-receptor (ER)-negative and (D-F) ER-positive isolated locoregional recurrence (ILRR). Interaction tests comparing the effect of chemotherapy (CT) for patients with ER-negative ILRR versus ER-positive ILRR are P_interaction = .013 for DFS (A v D); P_interaction = .034 for BCFI (B v E); and P_interaction = .53 for OS (C v F). No CT, not assigned to chemotherapy; HR, hazard ratio.